Seems that Microsoft has done some switching of how the Windows Scripting Host path is found.
This is a simple fix.
1. Install ASDM as you normally would
2. Right click on the shortcut.
3. In the "Target" line you will see a very long path to wscript.exe. Simply change this path to C:\Windows\System32\wscript.exe (leave the invisible.vbs run.bat on the end as these scripts are used to open ASDM).
4. Apply the change.
After doing this I was able to open ASDM normally and use it to update ASDM and AnyConnect files on my ASA.
Good luck!
